HCSGD entry for SLC25A2


1. General information

Official gene symbolSLC25A2
Entrez ID83884
Gene full namesolute carrier family 25 (mitochondrial carrier; ornithine transporter) member 2
Other gene symbolsORC2 ORNT2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000050Urea cycleTASbiological_process
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0006810TransportIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.65550150070.48288194600.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0645911121
GSE13712_SHEARUp0.1589957214
GSE13712_STATICDown-0.0751991341
GSE19018Up0.1331290757
GSE19899_A1Up0.1331085619
GSE19899_A2Down-0.0042091809
PubMed_21979375_A1Down-0.3552293222
PubMed_21979375_A2Up0.0743236635
GSE35957Up0.1714616962
GSE36640Up0.1180822685
GSE54402Down-0.0218353817
GSE9593Down-0.1008491766
GSE43922Up0.0274822011
GSE24585Down-0.1481431336
GSE37065Up0.0309912506
GSE28863_A1Down-0.2744823642
GSE28863_A2Up0.2753276433
GSE28863_A3Down-0.0299797341
GSE28863_A4Down-0.0012128743
GSE48662Down-0.2616819354

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-OrnithineDB00129 NUTR00043

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-378a-3pMIMAT0000732MIRT043873CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.