HCSGD entry for SETDB2
1. General information
| Official gene symbol | SETDB2 |
|---|---|
| Entrez ID | 83852 |
| Gene full name | SET domain, bifurcated 2 |
| Other gene symbols | C13orf4 CLLD8 CLLL8 KMT1F |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001947 | Heart looping | ISS | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0007059 | Chromosome segregation | IMP | biological_process |
| GO:0007067 | Mitosis | IMP | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0018022 | Peptidyl-lysine methylation | IDA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | ISS | biological_process |
| GO:0046974 | Histone methyltransferase activity (H3-K9 specific) | IDA | molecular_function |
| GO:0051567 | Histone H3-K9 methylation | IDA | biological_process |
| GO:0070986 | Left/right axis specification | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9509427453 | 0.0409539227 | 0.9999902473 | 0.3814395612 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0817873208 |
| GSE13712_SHEAR | Up | 0.0299831683 |
| GSE13712_STATIC | Down | -0.0957133320 |
| GSE19018 | Down | -0.5052252606 |
| GSE19899_A1 | Down | -0.2043524111 |
| GSE19899_A2 | Down | -0.8303770884 |
| PubMed_21979375_A1 | Down | -0.4164120886 |
| PubMed_21979375_A2 | Down | -0.6182091890 |
| GSE35957 | Down | -0.2744284280 |
| GSE36640 | Up | 0.1106270768 |
| GSE54402 | Down | -0.7915436256 |
| GSE9593 | Up | 0.1448880594 |
| GSE43922 | Down | -0.5836098771 |
| GSE24585 | Up | 0.2572706592 |
| GSE37065 | Up | 0.2566032194 |
| GSE28863_A1 | Down | -0.0682046033 |
| GSE28863_A2 | Down | -0.0430394509 |
| GSE28863_A3 | Down | -0.4476888296 |
| GSE28863_A4 | Down | -0.0074359728 |
| GSE48662 | Up | 0.0904574889 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
