HCSGD entry for CASP5
1. General information
| Official gene symbol | CASP5 |
|---|---|
| Entrez ID | 838 |
| Gene full name | caspase 5, apoptosis-related cysteine peptidase |
| Other gene symbols | ICE(rel)III ICEREL-III ICH-3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004197 | Cysteine-type endopeptidase activity | IEA | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0008234 | Cysteine-type peptidase activity | TAS | molecular_function |
| GO:0042981 | Regulation of apoptotic process | IEA | biological_process |
| GO:0071260 | Cellular response to mechanical stimulus | IEP | biological_process |
| GO:0072558 | NLRP1 inflammasome complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4803197257 | 0.8460141028 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0133980294 |
| GSE13712_SHEAR | Up | 0.0791811304 |
| GSE13712_STATIC | Down | -0.0492696929 |
| GSE19018 | Down | -0.0862478427 |
| GSE19899_A1 | Up | 0.1126084604 |
| GSE19899_A2 | Up | 0.0455190516 |
| PubMed_21979375_A1 | Up | 0.2141967252 |
| PubMed_21979375_A2 | Up | 0.1415599792 |
| GSE35957 | Up | 0.0952481100 |
| GSE36640 | Up | 0.1993751737 |
| GSE54402 | Up | 0.0824058042 |
| GSE9593 | Down | -0.2177392519 |
| GSE43922 | Up | 0.0079766372 |
| GSE24585 | Up | 0.2921452476 |
| GSE37065 | Up | 0.1266254984 |
| GSE28863_A1 | Down | -0.0307446013 |
| GSE28863_A2 | Up | 0.1354781588 |
| GSE28863_A3 | Up | 0.0845818237 |
| GSE28863_A4 | Up | 0.0079732694 |
| GSE48662 | Down | -0.2343104839 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
