HCSGD entry for MAD1L1

1. General information

Official gene symbolMAD1L1
Entrez ID8379
Gene full nameMAD1 mitotic arrest deficient-like 1 (yeast)
Other gene symbolsMAD1 PIG9 TP53I9 TXBP181
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000089Mitotic metaphaseNASbiological_process
GO:0000090Mitotic anaphaseNASbiological_process
GO:0000093Mitotic telophaseNASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000776KinetochoreIDAcellular_component
GO:0000777Condensed chromosome kinetochoreIEAcellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005643Nuclear poreIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIDAcellular_component
GO:0005813CentrosomeNAScellular_component
GO:0005819SpindleNAScellular_component
GO:0005829CytosolTAScellular_component
GO:0007067MitosisIEAbiological_process
GO:0007093Mitotic cell cycle checkpointNASbiological_process
GO:0007094Mitotic spindle assembly checkpointIEA TASbiological_process
GO:0015629Actin cytoskeletonIDAcellular_component
GO:0072686Mitotic spindleIDAcellular_component
GO:0090235Regulation of metaphase plate congressionIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05216418830.40334978910.50021057801.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2527979499
GSE13712_SHEARDown-0.5544117100
GSE13712_STATICUp0.3209297563
GSE19018Up0.2277484878
GSE19899_A1Up0.0840166766
GSE19899_A2Down-0.0256136280
PubMed_21979375_A1Up1.5636656600
PubMed_21979375_A2Up1.4571304388
GSE35957Down-1.4466820030
GSE36640Up0.0676516389
GSE54402Up0.1853380564
GSE9593Up0.4391220075
GSE43922Up0.0322065832
GSE24585Down-0.0008473712
GSE37065Down-0.1475801839
GSE28863_A1Down-0.5904736010
GSE28863_A2Down-0.2323279596
GSE28863_A3Up0.2605856020
GSE28863_A4Up0.1840825219
GSE48662Up0.4272515891

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-149-5pMIMAT0000450MIRT045498CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050540CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.