HCSGD entry for HYAL3


1. General information

Official gene symbolHYAL3
Entrez ID8372
Gene full namehyaluronoglucosaminidase 3
Other gene symbolsHYAL-3 LUCA-3 LUCA3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001618Virus receptor activityIDAmolecular_function
GO:0004415Hyalurononglucosaminidase activityIDA IEAmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005764LysosomeIDAcellular_component
GO:0005975Carbohydrate metabolic processIEAbiological_process
GO:0006954Inflammatory responseIDAbiological_process
GO:0009615Response to virusIDA IEAbiological_process
GO:0030214Hyaluronan catabolic processIDAbiological_process
GO:0031410Cytoplasmic vesicleIDAcellular_component
GO:0033906Hyaluronoglucuronidase activityIDAmolecular_function
GO:0046677Response to antibioticIEPbiological_process
GO:0051216Cartilage developmentIEPbiological_process
GO:0071347Cellular response to interleukin-1IDAbiological_process
GO:0071356Cellular response to tumor necrosis factorIEPbiological_process
GO:0071493Cellular response to UV-BIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.02037613690.99487907370.34344811261.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3007761870
GSE13712_SHEARUp0.4712410293
GSE13712_STATICUp0.3273520375
GSE19018Up0.1465505886
GSE19899_A1Up0.1036718500
GSE19899_A2Up0.7853202836
PubMed_21979375_A1Up0.8613529173
PubMed_21979375_A2Up0.4977284397
GSE35957Down-0.0242866567
GSE36640Up0.7388932263
GSE54402Down-0.0523302789
GSE9593Up0.5176169342
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.1388866378

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031666ProteomicsFunctional MTI (Weak)18668040
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.