HCSGD entry for PUS3
1. General information
| Official gene symbol | PUS3 |
|---|---|
| Entrez ID | 83480 |
| Gene full name | pseudouridylate synthase 3 |
| Other gene symbols | 2610020J05Rik |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0009982 | Pseudouridine synthase activity | IEA | molecular_function |
| GO:0031119 | TRNA pseudouridine synthesis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0148604042 | 0.4158502678 | 0.3036806677 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3835859025 |
| GSE13712_SHEAR | Down | -0.3710276319 |
| GSE13712_STATIC | Up | 0.1353434109 |
| GSE19018 | Down | -0.6752020788 |
| GSE19899_A1 | Up | 1.1210871751 |
| GSE19899_A2 | Up | 1.2739651345 |
| PubMed_21979375_A1 | Up | 1.5552667948 |
| PubMed_21979375_A2 | Up | 1.5723548724 |
| GSE35957 | Down | -0.5238381917 |
| GSE36640 | Up | 0.0625036922 |
| GSE54402 | Up | 0.5859184182 |
| GSE9593 | Down | -0.0228598185 |
| GSE43922 | Up | 0.7981147424 |
| GSE24585 | Down | -0.6022247356 |
| GSE37065 | Up | 0.2869738739 |
| GSE28863_A1 | Down | -0.1864832067 |
| GSE28863_A2 | Down | -0.1530275277 |
| GSE28863_A3 | Down | -0.2040351670 |
| GSE28863_A4 | Up | 0.0424995813 |
| GSE48662 | Up | 0.0466355108 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022366 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042525 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
