HCSGD entry for ARHGAP24

1. General information

Official gene symbolARHGAP24
Entrez ID83478
Gene full nameRho GTPase activating protein 24
Other gene symbolsFILGAP RC-GAP72 RCGAP72 p73 p73RhoGAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0005096GTPase activator activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005925Focal adhesionIEAcellular_component
GO:0007165Signal transductionIEAbiological_process
GO:0007264Small GTPase mediated signal transductionTASbiological_process
GO:0030154Cell differentiationIEAbiological_process
GO:0030675Rac GTPase activator activityIEAmolecular_function
GO:0032863Activation of Rac GTPase activityIEAbiological_process
GO:0035021Negative regulation of Rac protein signal transductionIEAbiological_process
GO:0035313Wound healing, spreading of epidermal cellsIEAbiological_process
GO:0042995Cell projectionIEAcellular_component
GO:0051056Regulation of small GTPase mediated signal transductionTASbiological_process
GO:1900028Negative regulation of ruffle assemblyIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00427950310.95252960750.17602159261.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3886025285
GSE13712_SHEARUp0.6379971866
GSE13712_STATICUp0.2813990151
GSE19018Down-0.1229650037
GSE19899_A1Up0.0279510276
GSE19899_A2Up1.6477064476
PubMed_21979375_A1Up1.0482500869
PubMed_21979375_A2Up0.7246577154
GSE35957Up0.1091865253
GSE36640Up1.3656705000
GSE54402Up1.4197146993
GSE9593Up0.9015496146
GSE43922Up0.7291527603
GSE24585Up0.3770796737
GSE37065Up0.0332765799
GSE28863_A1Up0.0428952320
GSE28863_A2Down-0.3140281933
GSE28863_A3Down-0.2666089218
GSE28863_A4Down-0.2891881347
GSE48662Down-0.2347793702

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.