HCSGD entry for DOHH
1. General information
| Official gene symbol | DOHH |
|---|---|
| Entrez ID | 83475 |
| Gene full name | deoxyhypusine hydroxylase/monooxygenase |
| Other gene symbols | HLRC1 hDOHH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008612 | Peptidyl-lysine modification to hypusine | IMP TAS | biological_process |
| GO:0019135 | Deoxyhypusine monooxygenase activity | IMP TAS | molecular_function |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2738022757 | 0.9032018084 | 0.9702713190 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0440514734 |
| GSE13712_SHEAR | Down | -0.0046920581 |
| GSE13712_STATIC | Up | 0.1628386928 |
| GSE19018 | Up | 0.0731162683 |
| GSE19899_A1 | Up | 0.0035141115 |
| GSE19899_A2 | Up | 0.3917373468 |
| PubMed_21979375_A1 | Up | 0.6585148944 |
| PubMed_21979375_A2 | Down | -0.1372439546 |
| GSE35957 | Down | -0.1011547341 |
| GSE36640 | Down | -0.2307479995 |
| GSE54402 | Up | 0.2891243463 |
| GSE9593 | Up | 0.1581955415 |
| GSE43922 | Up | 0.0510174060 |
| GSE24585 | Down | -0.1195531788 |
| GSE37065 | Down | -0.1006076838 |
| GSE28863_A1 | Down | -0.0897632220 |
| GSE28863_A2 | Down | -0.0132069992 |
| GSE28863_A3 | Up | 0.1500467501 |
| GSE28863_A4 | Up | 0.2227382131 |
| GSE48662 | Up | 0.6143026982 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-331-3p | MIMAT0000760 | MIRT006887 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 22908221 |
| hsa-miR-642a-5p | MIMAT0003312 | MIRT006888 | Luciferase reporter assay//qRT-PCR//Western blot | Functional MTI | 22908221 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
