HCSGD entry for HIST1H2AC
1. General information
| Official gene symbol | HIST1H2AC |
|---|---|
| Entrez ID | 8334 |
| Gene full name | histone cluster 1, H2ac |
| Other gene symbols | H2A/l H2AFL dJ221C16.4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000786 | Nucleosome | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006334 | Nucleosome assembly | IEA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000547320 | 0.8279310740 | 0.0195364865 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 4.3659723584 |
| GSE13712_SHEAR | Up | 0.6768869801 |
| GSE13712_STATIC | Up | 1.6518753815 |
| GSE19018 | Up | 1.5405510198 |
| GSE19899_A1 | Up | 1.7490933501 |
| GSE19899_A2 | Up | 1.2993740600 |
| PubMed_21979375_A1 | Up | 0.5924706323 |
| PubMed_21979375_A2 | Up | 0.9215510343 |
| GSE35957 | Up | 1.1830470204 |
| GSE36640 | Up | 5.4768254384 |
| GSE54402 | Up | 0.0988462072 |
| GSE9593 | Up | 1.8931165210 |
| GSE43922 | Down | -0.2975888759 |
| GSE24585 | Down | -0.3448899257 |
| GSE37065 | Down | -0.0165008109 |
| GSE28863_A1 | Down | -0.1607652173 |
| GSE28863_A2 | Up | 0.1663301922 |
| GSE28863_A3 | Down | -0.4683611457 |
| GSE28863_A4 | Down | -0.3079229722 |
| GSE48662 | Up | 0.8736242088 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025301 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027451 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-629-5p | MIMAT0004810 | MIRT037780 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-504-5p | MIMAT0002875 | MIRT041075 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-330-3p | MIMAT0000751 | MIRT043841 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046902 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049625 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
