HCSGD entry for FZD6

1. General information

Official gene symbolFZD6
Entrez ID8323
Gene full namefrizzled family receptor 6
Other gene symbolsFZ-6 FZ6 HFZ6 NDNC10
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIBAbiological_process
GO:0001736Establishment of planar polarityIBAbiological_process
GO:0001843Neural tube closureIBAbiological_process
GO:0001942Hair follicle developmentIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneISScellular_component
GO:0007199G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerIBAbiological_process
GO:0007275Multicellular organismal developmentIEAbiological_process
GO:0007409AxonogenesisIBAbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0016327Apicolateral plasma membraneIBAcellular_component
GO:0017147Wnt-protein bindingIBA ISSmolecular_function
GO:0030165PDZ domain bindingIBAmolecular_function
GO:0030168Platelet activationIEAbiological_process
GO:0031625Ubiquitin protein ligase bindingIPImolecular_function
GO:0032589Neuron projection membraneIBAcellular_component
GO:0033278Cell proliferation in midbrainIBAbiological_process
GO:0035567Non-canonical Wnt signaling pathwayIDAbiological_process
GO:0042472Inner ear morphogenesisIBAbiological_process
GO:0042813Wnt-activated receptor activityIDA IEAmolecular_function
GO:0043433Negative regulation of sequence-specific DNA binding transcription factor activityIDAbiological_process
GO:0045177Apical part of cellIBAcellular_component
GO:0060071Wnt signaling pathway, planar cell polarity pathwayIEAbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.45581325180.00289877280.99999024730.1074195499

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.9771730935
GSE13712_SHEARDown-0.7315676815
GSE13712_STATICDown-0.0722621751
GSE19018Up0.1525818019
GSE19899_A1Down-0.7846274875
GSE19899_A2Down-0.6610440050
PubMed_21979375_A1Down-1.5959568408
PubMed_21979375_A2Down-0.3380472063
GSE35957Up0.9236057414
GSE36640Up0.1185911836
GSE54402Down-0.8312122369
GSE9593Up1.7633452649
GSE43922Down-0.2402167879
GSE24585Up0.5521815654
GSE37065Up0.5042119636
GSE28863_A1Down-0.9013488082
GSE28863_A2Down-0.3822813189
GSE28863_A3Down-0.9312874841
GSE28863_A4Down-0.2161008491
GSE48662Down-0.1965076378

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-101-3pMIMAT0000099MIRT027324SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.