HCSGD entry for FZD1

1. General information

Official gene symbolFZD1
Entrez ID8321
Gene full namefrizzled family receptor 1
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001934Positive regulation of protein phosphorylationIEAbiological_process
GO:0001944Vasculature developmentIBAbiological_process
GO:0003149Membranous septum morphogenesisIEAbiological_process
GO:0003150Muscular septum morphogenesisIEAbiological_process
GO:0003151Outflow tract morphogenesisIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005102Receptor bindingIPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0007199G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messengerIBAbiological_process
GO:0007223Wnt signaling pathway, calcium modulating pathwayIBAbiological_process
GO:0007267Cell-cell signalingIDAbiological_process
GO:0007409AxonogenesisIBAbiological_process
GO:0007420Brain developmentIBAbiological_process
GO:0008406Gonad developmentIBAbiological_process
GO:0009790Embryo developmentIBAbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0017147Wnt-protein bindingIPImolecular_function
GO:0030165PDZ domain bindingIPImolecular_function
GO:0030182Neuron differentiationISSbiological_process
GO:0030514Negative regulation of BMP signaling pathwayIBAbiological_process
GO:0030855Epithelial cell differentiationIBAbiological_process
GO:0032589Neuron projection membraneIBAcellular_component
GO:0035414Negative regulation of catenin import into nucleusIEAbiological_process
GO:0035425Autocrine signalingIDAbiological_process
GO:0042493Response to drugIMPbiological_process
GO:0042813Wnt-activated receptor activityIDAmolecular_function
GO:0044338Canonical Wnt signaling pathway involved in mesenchymal stem cell differentiationIMPbiological_process
GO:0044339Canonical Wnt signaling pathway involved in osteoblast differentiationIMPbiological_process
GO:0045177Apical part of cellIBAcellular_component
GO:0045892Negative regulation of transcription, DNA-templatedIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
GO:0048286Lung alveolus developmentIBAbiological_process
GO:0051091Positive regulation of sequence-specific DNA binding transcription factor activityIDAbiological_process
GO:0060022Hard palate developmentIEAbiological_process
GO:0060070Canonical Wnt signaling pathwayIDAbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIBAbiological_process
GO:0090179Planar cell polarity pathway involved in neural tube closureIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91306030930.03811670530.99999024730.3679023836

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2463000131
GSE13712_SHEARDown-0.3081215558
GSE13712_STATICDown-0.1298389870
GSE19018Down-0.2800000389
GSE19899_A1Up0.1774000116
GSE19899_A2Down-0.9638862478
PubMed_21979375_A1Down-0.6950299900
PubMed_21979375_A2Down-0.5277310548
GSE35957Up0.3818151318
GSE36640Down-0.4415722555
GSE54402Down-0.2495841791
GSE9593Down-0.7761036404
GSE43922Up0.0801818234
GSE24585Up0.1115138036
GSE37065Down-0.3617910581
GSE28863_A1Up0.1309231493
GSE28863_A2Up0.5243893714
GSE28863_A3Down-0.0447360751
GSE28863_A4Down-0.1932975963
GSE48662Up0.1400509657

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-204-5pMIMAT0000265MIRT005827Luciferase reporter assay//Microarray//qRT-PCRFunctional MTI21282569
hsa-miR-335-5pMIMAT0000765MIRT017459MicroarrayFunctional MTI (Weak)18185580
hsa-miR-215-5pMIMAT0000272MIRT024292MicroarrayFunctional MTI (Weak)19074876
hsa-miR-192-5pMIMAT0000222MIRT026323MicroarrayFunctional MTI (Weak)19074876
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.