HCSGD entry for BRAP
1. General information
| Official gene symbol | BRAP |
|---|---|
| Entrez ID | 8315 |
| Gene full name | BRCA1 associated protein |
| Other gene symbols | BRAP2 IMP RNF52 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | IDA | cellular_component |
| GO:0000165 | MAPK cascade | IDA | biological_process |
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0007265 | Ras protein signal transduction | IDA | biological_process |
| GO:0008139 | Nuclear localization sequence binding | IDA | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0009968 | Negative regulation of signal transduction | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0213932639 | 0.9871374872 | 0.3525680851 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4873232136 |
| GSE13712_SHEAR | Up | 0.2035242187 |
| GSE13712_STATIC | Up | 0.0397043188 |
| GSE19018 | Down | -0.1880078034 |
| GSE19899_A1 | Up | 0.0593658300 |
| GSE19899_A2 | Up | 0.6594705546 |
| PubMed_21979375_A1 | Up | 0.7953625698 |
| PubMed_21979375_A2 | Up | 0.5162979513 |
| GSE35957 | Down | -0.0676405424 |
| GSE36640 | Up | 0.4931978362 |
| GSE54402 | Up | 0.2367990967 |
| GSE9593 | Up | 0.0745050468 |
| GSE43922 | Up | 0.3435121550 |
| GSE24585 | Up | 0.2076000146 |
| GSE37065 | Up | 0.1359445729 |
| GSE28863_A1 | Up | 0.3746128314 |
| GSE28863_A2 | Up | 0.4195406168 |
| GSE28863_A3 | Down | -0.2586002595 |
| GSE28863_A4 | Up | 0.0709377248 |
| GSE48662 | Up | 0.1644116513 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT003364 | Reporter assay;Microarray | Non-Functional MTI | 20018759 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036070 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
