HCSGD entry for CAST
1. General information
| Official gene symbol | CAST |
|---|---|
| Entrez ID | 831 |
| Gene full name | calpastatin |
| Other gene symbols | BS-17 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004866 | Endopeptidase inhibitor activity | TAS | molecular_function |
| GO:0004869 | Cysteine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0010466 | Negative regulation of peptidase activity | IEA | biological_process |
| GO:0010951 | Negative regulation of endopeptidase activity | TAS | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0052548 | Regulation of endopeptidase activity | TAS | biological_process |
| GO:2000675 | Negative regulation of type B pancreatic cell apoptotic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2175644466 | 0.8442248851 | 0.8970987314 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0337058521 |
| GSE13712_SHEAR | Down | -0.1595144106 |
| GSE13712_STATIC | Down | -0.0453777521 |
| GSE19018 | Up | 0.5773321593 |
| GSE19899_A1 | Down | -0.0044255164 |
| GSE19899_A2 | Down | -0.0956972336 |
| PubMed_21979375_A1 | Up | 0.0966866787 |
| PubMed_21979375_A2 | Up | 0.3160066312 |
| GSE35957 | Up | 0.3036713935 |
| GSE36640 | Up | 0.2809167425 |
| GSE54402 | Down | -0.3686938828 |
| GSE9593 | Up | 0.3061915785 |
| GSE43922 | Up | 0.1851920341 |
| GSE24585 | Up | 0.0694349329 |
| GSE37065 | Up | 0.0490954087 |
| GSE28863_A1 | Up | 0.2080139288 |
| GSE28863_A2 | Up | 0.3556501970 |
| GSE28863_A3 | Down | -0.2220662822 |
| GSE28863_A4 | Down | -0.2462324069 |
| GSE48662 | Down | -0.1519127907 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Calcium | DB01373 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022430 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023661 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028450 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046826 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
