HCSGD entry for ARID1A
1. General information
| Official gene symbol | ARID1A |
|---|---|
| Entrez ID | 8289 |
| Gene full name | AT rich interactive domain 1A (SWI-like) |
| Other gene symbols | B120 BAF250 BAF250a BM029 C1orf4 ELD MRD14 OSA1 P270 SMARCF1 hELD hOSA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0000790 | Nuclear chromatin | IDA IEA | cellular_component |
| GO:0001843 | Neural tube closure | IEA | biological_process |
| GO:0003205 | Cardiac chamber development | IEA | biological_process |
| GO:0003408 | Optic cup formation involved in camera-type eye development | IEA | biological_process |
| GO:0003677 | DNA binding | IDA NAS | molecular_function |
| GO:0003713 | Transcription coactivator activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006337 | Nucleosome disassembly | IDA | biological_process |
| GO:0006338 | Chromatin remodeling | IDA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | NAS | biological_process |
| GO:0016514 | SWI/SNF complex | IDA IEA | cellular_component |
| GO:0016922 | Ligand-dependent nuclear receptor binding | IPI | molecular_function |
| GO:0030520 | Intracellular estrogen receptor signaling pathway | IDA | biological_process |
| GO:0030521 | Androgen receptor signaling pathway | IDA | biological_process |
| GO:0030900 | Forebrain development | IEA | biological_process |
| GO:0031491 | Nucleosome binding | IEA | molecular_function |
| GO:0042766 | Nucleosome mobilization | TAS | biological_process |
| GO:0042921 | Glucocorticoid receptor signaling pathway | IDA | biological_process |
| GO:0043044 | ATP-dependent chromatin remodeling | IEA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0048096 | Chromatin-mediated maintenance of transcription | TAS | biological_process |
| GO:0060674 | Placenta blood vessel development | IEA | biological_process |
| GO:0071564 | NpBAF complex | IEA ISS | cellular_component |
| GO:0071565 | NBAF complex | IEA ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3564836898 | 0.2727822043 | 0.9999902473 | 0.9987342329 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3414583092 |
| GSE13712_SHEAR | Up | 0.1339178575 |
| GSE13712_STATIC | Up | 0.1417725675 |
| GSE19018 | Down | -0.0249011440 |
| GSE19899_A1 | Down | -0.2495299460 |
| GSE19899_A2 | Up | 0.0374563357 |
| PubMed_21979375_A1 | Up | 0.4998517100 |
| PubMed_21979375_A2 | Up | 0.3149902670 |
| GSE35957 | Down | -0.0608357525 |
| GSE36640 | Down | -0.7258247309 |
| GSE54402 | Down | -0.1351729326 |
| GSE9593 | Down | -0.2006232512 |
| GSE43922 | Down | -0.0616616553 |
| GSE24585 | Up | 0.1443616116 |
| GSE37065 | Down | -0.0212849029 |
| GSE28863_A1 | Up | 0.5756563829 |
| GSE28863_A2 | Up | 0.5779741662 |
| GSE28863_A3 | Up | 0.3094634482 |
| GSE28863_A4 | Down | -0.2252237668 |
| GSE48662 | Down | -0.2312486231 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001385 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT004027 | Western blot | Non-Functional MTI | 19008416 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT004027 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024162 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027653 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036956 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038464 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-181a-2-3p | MIMAT0004558 | MIRT038669 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040907 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041580 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042203 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042943 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043438 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049171 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051608 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
