HCSGD entry for EPX
1. General information
| Official gene symbol | EPX |
|---|---|
| Entrez ID | 8288 |
| Gene full name | eosinophil peroxidase |
| Other gene symbols | EPO EPP EPX-PEN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002215 | Defense response to nematode | IEA | biological_process |
| GO:0004601 | Peroxidase activity | IEA | molecular_function |
| GO:0020037 | Heme binding | IEA | molecular_function |
| GO:0032693 | Negative regulation of interleukin-10 production | IEA | biological_process |
| GO:0032714 | Negative regulation of interleukin-5 production | IEA | biological_process |
| GO:0032753 | Positive regulation of interleukin-4 production | IEA | biological_process |
| GO:0042744 | Hydrogen peroxide catabolic process | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0072677 | Eosinophil migration | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7422611071 | 0.7250380343 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1021454039 |
| GSE13712_SHEAR | Down | -0.0808271102 |
| GSE13712_STATIC | Up | 0.0104868789 |
| GSE19018 | Up | 0.1324322907 |
| GSE19899_A1 | Down | -0.0458235092 |
| GSE19899_A2 | Up | 0.1521093815 |
| PubMed_21979375_A1 | Down | -0.2849552135 |
| PubMed_21979375_A2 | Up | 0.2017772698 |
| GSE35957 | Up | 0.2625377674 |
| GSE36640 | Up | 0.0486116466 |
| GSE54402 | Up | 0.0817553928 |
| GSE9593 | Up | 0.0140575720 |
| GSE43922 | Up | 0.1426326517 |
| GSE24585 | Down | -0.1425694802 |
| GSE37065 | Down | -0.0443931189 |
| GSE28863_A1 | Down | -0.1199500395 |
| GSE28863_A2 | Down | -0.0167254616 |
| GSE28863_A3 | Up | 0.1992885958 |
| GSE28863_A4 | Down | -0.0084343400 |
| GSE48662 | Down | -0.0559399804 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Melatonin | DB01065 | APRD00742 | DB08189 |
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
