HCSGD entry for KDM5D
1. General information
| Official gene symbol | KDM5D |
|---|---|
| Entrez ID | 8284 |
| Gene full name | lysine (K)-specific demethylase 5D |
| Other gene symbols | HY HYA JARID1D SMCY |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016706 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | IEA | molecular_function |
| GO:0032453 | Histone demethylase activity (H3-K4 specific) | IDA | molecular_function |
| GO:0034720 | Histone H3-K4 demethylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3707508301 | 0.2268632385 | 0.9999902473 | 0.9159790305 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3804548759 |
| GSE13712_SHEAR | Up | 0.2193462696 |
| GSE13712_STATIC | Down | -0.2703835499 |
| GSE19018 | Up | 0.2899001849 |
| GSE19899_A1 | Up | 0.0778646761 |
| GSE19899_A2 | Up | 0.0871886185 |
| PubMed_21979375_A1 | Up | 0.2618779603 |
| PubMed_21979375_A2 | Up | 0.0563435161 |
| GSE35957 | Down | -1.7154603186 |
| GSE36640 | Up | 0.0752406905 |
| GSE54402 | Down | -0.0410760344 |
| GSE9593 | Down | -0.4668362188 |
| GSE43922 | Up | 0.0174972232 |
| GSE24585 | Down | -0.0701454062 |
| GSE37065 | Up | 0.0948050964 |
| GSE28863_A1 | Up | 0.1379878871 |
| GSE28863_A2 | Down | -0.0305771353 |
| GSE28863_A3 | Down | -0.0091138496 |
| GSE28863_A4 | Down | -0.0976885977 |
| GSE48662 | Down | -0.4637870101 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Vitamin C | DB00126 | NUTR00001 | APRD00084 | EXPT00568 | DB09541 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018612 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029979 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
