HCSGD entry for TKTL1
1. General information
| Official gene symbol | TKTL1 |
|---|---|
| Entrez ID | 8277 |
| Gene full name | transketolase-like 1 |
| Other gene symbols | TKR TKT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004802 | Transketolase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006007 | Glucose catabolic process | TAS | biological_process |
| GO:0006772 | Thiamine metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7016887048 | 0.8398026367 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0657010776 |
| GSE13712_SHEAR | Up | 0.1648080581 |
| GSE13712_STATIC | Down | -0.0987240181 |
| GSE19018 | Up | 0.0763882978 |
| GSE19899_A1 | Down | -0.0085349676 |
| GSE19899_A2 | Up | 0.1251897292 |
| PubMed_21979375_A1 | Up | 0.0816551267 |
| PubMed_21979375_A2 | Up | 0.0517150235 |
| GSE35957 | Up | 0.1170697091 |
| GSE36640 | Down | -0.0231200018 |
| GSE54402 | Up | 0.0106550715 |
| GSE9593 | Up | 0.0461165361 |
| GSE43922 | Down | -0.1147654523 |
| GSE24585 | Down | -0.0160786080 |
| GSE37065 | Down | -0.0662864905 |
| GSE28863_A1 | Down | -0.0055350154 |
| GSE28863_A2 | Up | 0.0121824972 |
| GSE28863_A3 | Up | 0.1670143889 |
| GSE28863_A4 | Up | 0.0689035551 |
| GSE48662 | Down | -0.0405265617 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017410 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
