HCSGD entry for KDM5C
1. General information
| Official gene symbol | KDM5C |
|---|---|
| Entrez ID | 8242 |
| Gene full name | lysine (K)-specific demethylase 5C |
| Other gene symbols | DXS1272E JARID1C MRXJ MRXSCJ MRXSJ SMCX XE169 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016706 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | IEA | molecular_function |
| GO:0032453 | Histone demethylase activity (H3-K4 specific) | IDA | molecular_function |
| GO:0034720 | Histone H3-K4 demethylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0097023973 | 0.9838793625 | 0.2513551181 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0595046449 |
| GSE13712_SHEAR | Down | -0.0798779408 |
| GSE13712_STATIC | Up | 0.0264781004 |
| GSE19018 | Down | -0.1021682202 |
| GSE19899_A1 | Up | 0.2413499232 |
| GSE19899_A2 | Up | 0.7098135937 |
| PubMed_21979375_A1 | Up | 1.4147441032 |
| PubMed_21979375_A2 | Up | 1.5409638491 |
| GSE35957 | Down | -0.0440953260 |
| GSE36640 | Up | 0.2005353901 |
| GSE54402 | Up | 0.4846175347 |
| GSE9593 | Up | 0.1831984989 |
| GSE43922 | Up | 0.6915226164 |
| GSE24585 | Up | 0.2524935470 |
| GSE37065 | Up | 0.0240406952 |
| GSE28863_A1 | Up | 0.7570199140 |
| GSE28863_A2 | Up | 0.4044661785 |
| GSE28863_A3 | Down | -0.2579735942 |
| GSE28863_A4 | Up | 0.0066326032 |
| GSE48662 | Up | 0.2877965124 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036342 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-605-5p | MIMAT0003273 | MIRT040478 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041792 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-425-3p | MIMAT0001343 | MIRT042424 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042989 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-3p | MIMAT0000732 | MIRT043887 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044496 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050192 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
