HCSGD entry for CAPN1
1. General information
| Official gene symbol | CAPN1 |
|---|---|
| Entrez ID | 823 |
| Gene full name | calpain 1, (mu/I) large subunit |
| Other gene symbols | CANP CANP1 CANPL1 muCANP muCL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004198 | Calcium-dependent cysteine-type endopeptidase activity | IEA ISS | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA ISS | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | TAS | biological_process |
| GO:0032801 | Receptor catabolic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2272640363 | 0.5550159112 | 0.9086763937 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2360979822 |
| GSE13712_SHEAR | Down | -0.1760407093 |
| GSE13712_STATIC | Down | -0.1101776102 |
| GSE19018 | Up | 0.1525574113 |
| GSE19899_A1 | Down | -0.4548303403 |
| GSE19899_A2 | Up | 0.6741441420 |
| PubMed_21979375_A1 | Up | 0.2460841130 |
| PubMed_21979375_A2 | Up | 0.4171068742 |
| GSE35957 | Up | 0.0690794361 |
| GSE36640 | Down | -0.0159634944 |
| GSE54402 | Down | -0.0004634005 |
| GSE9593 | Down | -0.0245951590 |
| GSE43922 | Down | -0.2566610097 |
| GSE24585 | Up | 0.0546253572 |
| GSE37065 | Down | -0.1938290068 |
| GSE28863_A1 | Up | 0.2044753020 |
| GSE28863_A2 | Up | 0.2565068111 |
| GSE28863_A3 | Down | -0.4648308153 |
| GSE28863_A4 | Up | 0.0126475766 |
| GSE48662 | Up | 0.5530884900 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| N-[N-[1-Hydroxycarboxyethyl-Carbonyl]Leucylamino-Butyl]-Guanidine | DB04276 | EXPT01317 |
| CBZ-LEU-LEU-TYR-CH2F | DB04653 | - |
| (2S)-4-METHYL-2-(3-PHENYLTHIOUREIDO)-N-((3S)-TETRAHYDRO-2-HYDROXY-3-FURANYL)PENTANAMIDE | DB07627 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023560 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025341 | Proteomics | Functional MTI (Weak) | 21566225 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
