HCSGD entry for AKAP17A
1. General information
| Official gene symbol | AKAP17A |
|---|---|
| Entrez ID | 8227 |
| Gene full name | A kinase (PRKA) anchor protein 17A |
| Other gene symbols | 721P AKAP-17A CCDC133 CXYorf3 DXYS155E PRKA17A SFRS17A XE7 XE7Y |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005681 | Spliceosomal complex | IEA | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0042113 | B cell activation | NAS | biological_process |
| GO:0043484 | Regulation of RNA splicing | IMP | biological_process |
| GO:0051018 | Protein kinase A binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2426025911 | 0.8728458797 | 0.9299221123 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2067766116 |
| GSE13712_SHEAR | Down | -0.4277568206 |
| GSE13712_STATIC | Down | -0.0434175398 |
| GSE19018 | Down | -0.0369025222 |
| GSE19899_A1 | Up | 0.0520854770 |
| GSE19899_A2 | Up | 0.8293790934 |
| PubMed_21979375_A1 | Up | 0.6972161474 |
| PubMed_21979375_A2 | Up | 0.7629059081 |
| GSE35957 | Down | -0.4025321904 |
| GSE36640 | Up | 0.2010297497 |
| GSE54402 | Up | 0.1292675736 |
| GSE9593 | Down | -0.1900221615 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0153800208 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7a-5p | MIMAT0000062 | MIRT052445 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
