HCSGD entry for SYMPK
1. General information
| Official gene symbol | SYMPK |
|---|---|
| Entrez ID | 8189 |
| Gene full name | symplekin |
| Other gene symbols | SPK SYM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005923 | Tight junction | IEA | cellular_component |
| GO:0006378 | MRNA polyadenylation | IMP | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0035307 | Positive regulation of protein dephosphorylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7377458759 | 0.3362015387 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0067117068 |
| GSE13712_SHEAR | Up | 0.0401226618 |
| GSE13712_STATIC | Down | -0.0497672953 |
| GSE19018 | Up | 0.0651096111 |
| GSE19899_A1 | Down | -0.0623726971 |
| GSE19899_A2 | Down | -0.1519779473 |
| PubMed_21979375_A1 | Down | -0.2056244158 |
| PubMed_21979375_A2 | Down | -0.1118706524 |
| GSE35957 | Down | -0.1420959308 |
| GSE36640 | Down | -0.5129551409 |
| GSE54402 | Down | -0.0192104715 |
| GSE9593 | Down | -0.2939247958 |
| GSE43922 | Up | 0.0749617243 |
| GSE24585 | Down | -0.4427076738 |
| GSE37065 | Up | 0.0033182922 |
| GSE28863_A1 | Up | 0.2514963292 |
| GSE28863_A2 | Up | 0.3002611094 |
| GSE28863_A3 | Down | -0.0583819226 |
| GSE28863_A4 | Down | -0.0973002716 |
| GSE48662 | Up | 0.8126478415 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT023496 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-940 | MIMAT0004983 | MIRT036616 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-760 | MIMAT0004957 | MIRT036753 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037562 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040725 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041533 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047571 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
