HCSGD entry for ISG20L2


1. General information

Official gene symbolISG20L2
Entrez ID81875
Gene full nameinterferon stimulated exonuclease gene 20kDa-like 2
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0004527Exonuclease activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIEAcellular_component
GO:0042254Ribosome biogenesisIEAbiological_process
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08000825200.70278876560.59589620831.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0602191146
GSE13712_SHEARUp0.2092698080
GSE13712_STATICUp0.1497022605
GSE19018Down-0.2046200037
GSE19899_A1Up0.3969806962
GSE19899_A2Up0.7408881155
PubMed_21979375_A1Up0.7730052098
PubMed_21979375_A2Up1.1664219453
GSE35957Down-0.1136508126
GSE36640Up0.0410679338
GSE54402Up0.4530504737
GSE9593Down-0.3484024552
GSE43922Up0.7270396454
GSE24585Down-0.6306648706
GSE37065Down-0.1361915077
GSE28863_A1Down-0.1133575426
GSE28863_A2Up0.1967684448
GSE28863_A3Down-0.0130133695
GSE28863_A4Down-0.1925729559
GSE48662Down-0.0602345565

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-3pMIMAT0004950MIRT036818CLASHFunctional MTI (Weak)23622248
hsa-miR-222-3pMIMAT0000279MIRT046613CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.