HCSGD entry for RNF146
1. General information
| Official gene symbol | RNF146 |
|---|---|
| Entrez ID | 81847 |
| Gene full name | ring finger protein 146 |
| Other gene symbols | RP3-351K20.1 dJ351K20.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IMP | biological_process |
| GO:0051865 | Protein autoubiquitination | IDA | biological_process |
| GO:0070936 | Protein K48-linked ubiquitination | IMP | biological_process |
| GO:0072572 | Poly-ADP-D-ribose binding | IDA | molecular_function |
| GO:0090263 | Positive regulation of canonical Wnt signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2926620227 | 0.5199482466 | 0.9929307940 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5385189281 |
| GSE13712_SHEAR | Down | -0.2269865631 |
| GSE13712_STATIC | Down | -0.2889116936 |
| GSE19018 | Up | 0.0459829535 |
| GSE19899_A1 | Down | -0.0162517909 |
| GSE19899_A2 | Up | 0.1830353604 |
| PubMed_21979375_A1 | Down | -0.2506614882 |
| PubMed_21979375_A2 | Down | -0.2866307617 |
| GSE35957 | Up | 0.3662992293 |
| GSE36640 | Up | 0.4355523956 |
| GSE54402 | Down | -0.0104384690 |
| GSE9593 | Up | 0.6169555610 |
| GSE43922 | Down | -0.0553205455 |
| GSE24585 | Up | 0.2600677684 |
| GSE37065 | Up | 0.1611981109 |
| GSE28863_A1 | Up | 0.0381459798 |
| GSE28863_A2 | Up | 0.1619287345 |
| GSE28863_A3 | Down | -0.1286484391 |
| GSE28863_A4 | Down | -0.1937355457 |
| GSE48662 | Down | -0.1680723817 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-17-5p | MIMAT0000070 | MIRT051033 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
