HCSGD entry for SF3A2


1. General information

Official gene symbolSF3A2
Entrez ID8175
Gene full namesplicing factor 3a, subunit 2, 66kDa
Other gene symbolsPRP11 PRPF11 SAP62 SF3a66
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000389MRNA 3'-splice site recognitionTASbiological_process
GO:0000398MRNA splicing, via spliceosomeIC TASbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005681Spliceosomal complexIDAcellular_component
GO:0006397MRNA processingIMPbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0030532Small nuclear ribonucleoprotein complexTAScellular_component
GO:0071013Catalytic step 2 spliceosomeIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.17861644310.14706126670.82869802640.7410342649

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1679215057
GSE13712_SHEARUp0.0564982763
GSE13712_STATICDown-0.2365415965
GSE19018Up0.1438824859
GSE19899_A1Down-0.0507221463
GSE19899_A2Up0.7061585437
PubMed_21979375_A1Down-0.4711526788
PubMed_21979375_A2Up1.5277147626
GSE35957Down-0.6672584710
GSE36640Down-0.8131708213
GSE54402Down-0.1370585927
GSE9593Down-0.5981614065
GSE43922Down-0.0005739725
GSE24585Down-0.0937331480
GSE37065Down-0.3336386147
GSE28863_A1Up0.0785592255
GSE28863_A2Up0.1234039084
GSE28863_A3Up0.4658612595
GSE28863_A4Up0.1640221736
GSE48662Up0.3856467417

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.