HCSGD entry for PLA2G12A
1. General information
| Official gene symbol | PLA2G12A |
|---|---|
| Entrez ID | 81579 |
| Gene full name | phospholipase A2, group XIIA |
| Other gene symbols | GXII PLA2G12 ROSSY |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004623 | Phospholipase A2 activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | IEA NAS TAS | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0006644 | Phospholipid metabolic process | TAS | biological_process |
| GO:0006654 | Phosphatidic acid biosynthetic process | TAS | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0016042 | Lipid catabolic process | IEA | biological_process |
| GO:0036148 | Phosphatidylglycerol acyl-chain remodeling | TAS | biological_process |
| GO:0036149 | Phosphatidylinositol acyl-chain remodeling | TAS | biological_process |
| GO:0036150 | Phosphatidylserine acyl-chain remodeling | TAS | biological_process |
| GO:0036151 | Phosphatidylcholine acyl-chain remodeling | TAS | biological_process |
| GO:0036152 | Phosphatidylethanolamine acyl-chain remodeling | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046474 | Glycerophospholipid biosynthetic process | TAS | biological_process |
| GO:0047498 | Calcium-dependent phospholipase A2 activity | NAS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3921342958 | 0.1880054443 | 0.9999902473 | 0.8403974198 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0239290226 |
| GSE13712_SHEAR | Down | -0.4859720327 |
| GSE13712_STATIC | Up | 0.0506787797 |
| GSE19018 | Up | 0.6270526255 |
| GSE19899_A1 | Down | -0.2290262518 |
| GSE19899_A2 | Up | 0.0916617727 |
| PubMed_21979375_A1 | Down | -0.2554859962 |
| PubMed_21979375_A2 | Down | -0.0940174859 |
| GSE35957 | Up | 0.4646687088 |
| GSE36640 | Up | 1.2150560939 |
| GSE54402 | Down | -0.7101776325 |
| GSE9593 | Up | 0.3563922224 |
| GSE43922 | Down | -0.0593002304 |
| GSE24585 | Up | 0.0571559802 |
| GSE37065 | Down | -0.1524026778 |
| GSE28863_A1 | Up | 0.0103027917 |
| GSE28863_A2 | Up | 0.0338605873 |
| GSE28863_A3 | Down | -0.3373334527 |
| GSE28863_A4 | Down | -0.3129323460 |
| GSE48662 | Up | 0.0280405000 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040676 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
