HCSGD entry for HM13


1. General information

Official gene symbolHM13
Entrez ID81502
Gene full namehistocompatibility (minor) 13
Other gene symbolsH13 IMP1 IMPAS IMPAS-1 MSTP086 PSENL3 PSL3 SPP SPPL1 dJ324O17.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumISScellular_component
GO:0005791Rough endoplasmic reticulumIDAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006509Membrane protein ectodomain proteolysisIMPbiological_process
GO:0008233Peptidase activityIDAmolecular_function
GO:0009986Cell surfaceISScellular_component
GO:0031293Membrane protein intracellular domain proteolysisIMPbiological_process
GO:0033619Membrane protein proteolysisIDAbiological_process
GO:0042500Aspartic endopeptidase activity, intramembrane cleavingIMPmolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0071458Integral component of cytoplasmic side of endoplasmic reticulum membraneIDAcellular_component
GO:0071556Integral component of lumenal side of endoplasmic reticulum membraneIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11479524710.94642345280.69636453101.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0382251470
GSE13712_SHEARUp0.0068783070
GSE13712_STATICUp0.1150693433
GSE19018Up0.0061464736
GSE19899_A1Up0.2282228184
GSE19899_A2Up0.5474841418
PubMed_21979375_A1Up0.3043328279
PubMed_21979375_A2Up0.2782035441
GSE35957Down-0.0773815468
GSE36640Up0.5712921211
GSE54402Up0.2749975959
GSE9593Up0.1728906373
GSE43922Up0.5343966176
GSE24585Down-0.1429143993
GSE37065Up0.1911569030
GSE28863_A1Up0.0403346831
GSE28863_A2Down-0.2069314452
GSE28863_A3Down-0.3112717798
GSE28863_A4Down-0.0284246619
GSE48662Up0.1183805416

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-744-5pMIMAT0004945MIRT037716CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041269CLASHFunctional MTI (Weak)23622248
hsa-miR-16-5pMIMAT0000069MIRT051212CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.