HCSGD entry for WNT5B
1. General information
| Official gene symbol | WNT5B |
|---|---|
| Entrez ID | 81029 |
| Gene full name | wingless-type MMTV integration site family, member 5B |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002062 | Chondrocyte differentiation | IEP | biological_process |
| GO:0005102 | Receptor binding | IEA IPI | molecular_function |
| GO:0005109 | Frizzled binding | IBA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0005615 | Extracellular space | NAS | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | TAS | cellular_component |
| GO:0005796 | Golgi lumen | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0009986 | Cell surface | IEA | cellular_component |
| GO:0016055 | Wnt signaling pathway | IDA IEA IMP | biological_process |
| GO:0030182 | Neuron differentiation | IBA ISS | biological_process |
| GO:0030335 | Positive regulation of cell migration | IDA | biological_process |
| GO:0042060 | Wound healing | IEA | biological_process |
| GO:0045165 | Cell fate commitment | IBA | biological_process |
| GO:0045444 | Fat cell differentiation | NAS | biological_process |
| GO:0045600 | Positive regulation of fat cell differentiation | IEA | biological_process |
| GO:0070307 | Lens fiber cell development | ISS | biological_process |
| GO:0071300 | Cellular response to retinoic acid | ISS | biological_process |
| GO:0090090 | Negative regulation of canonical Wnt signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1012080012 | 0.3761199536 | 0.6623827492 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2947969182 |
| GSE13712_SHEAR | Up | 0.0711862065 |
| GSE13712_STATIC | Down | -0.0545177714 |
| GSE19018 | Up | 0.5718800400 |
| GSE19899_A1 | Down | -0.2075153898 |
| GSE19899_A2 | Up | 0.0952358599 |
| PubMed_21979375_A1 | Down | -1.0528124368 |
| PubMed_21979375_A2 | Down | -0.7118458120 |
| GSE35957 | Down | -0.0017879780 |
| GSE36640 | Up | 1.1832524073 |
| GSE54402 | Down | -0.0940640776 |
| GSE9593 | Up | 1.6950397110 |
| GSE43922 | Up | 0.0236845016 |
| GSE24585 | Down | -0.1035214598 |
| GSE37065 | Down | -0.0467172289 |
| GSE28863_A1 | Down | -0.1132763805 |
| GSE28863_A2 | Up | 0.0136584272 |
| GSE28863_A3 | Down | -0.1410045832 |
| GSE28863_A4 | Up | 0.0914007340 |
| GSE48662 | Up | 0.0791421222 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022886 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045371 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
