HCSGD entry for FXR1
1. General information
| Official gene symbol | FXR1 |
|---|---|
| Entrez ID | 8087 |
| Gene full name | fragile X mental retardation, autosomal homolog 1 |
| Other gene symbols | FXR1P |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002151 | G-quadruplex RNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA TAS | molecular_function |
| GO:0003730 | MRNA 3'-UTR binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005730 | Nucleolus | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005844 | Polysome | IEA | cellular_component |
| GO:0006915 | Apoptotic process | TAS | biological_process |
| GO:0007517 | Muscle organ development | IEA | biological_process |
| GO:0017148 | Negative regulation of translation | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0043034 | Costamere | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5410023137 | 0.3855103302 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0338817595 |
| GSE13712_SHEAR | Down | -0.2401188524 |
| GSE13712_STATIC | Down | -0.1437745731 |
| GSE19018 | Up | 0.1835530660 |
| GSE19899_A1 | Down | -0.1638525480 |
| GSE19899_A2 | Down | -0.1741474380 |
| PubMed_21979375_A1 | Down | -0.1219665543 |
| PubMed_21979375_A2 | Down | -0.5084996609 |
| GSE35957 | Up | 0.0339306663 |
| GSE36640 | Down | -0.2018735913 |
| GSE54402 | Down | -0.1093793517 |
| GSE9593 | Down | -0.0360715724 |
| GSE43922 | Down | -0.2512494799 |
| GSE24585 | Up | 0.3307913502 |
| GSE37065 | Up | 0.0535462366 |
| GSE28863_A1 | Up | 0.7269726058 |
| GSE28863_A2 | Up | 0.5801754146 |
| GSE28863_A3 | Up | 0.0336634707 |
| GSE28863_A4 | Down | -0.0375918659 |
| GSE48662 | Up | 0.0490310726 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022502 | Proteomics | Functional MTI (Weak) | 18668037 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025398 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028542 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045421 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045986 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
