HCSGD entry for AAAS


1. General information

Official gene symbolAAAS
Entrez ID8086
Gene full nameachalasia, adrenocortical insufficiency, alacrimia
Other gene symbolsAAA AAASb ADRACALA ADRACALIN ALADIN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0003674Molecular_functionNDmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005635Nuclear envelopeTAScellular_component
GO:0005643Nuclear poreIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005813CentrosomeIDAcellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006913Nucleocytoplasmic transportIDAbiological_process
GO:0007077Mitotic nuclear envelope disassemblyTASbiological_process
GO:0007612LearningIEAbiological_process
GO:0008645Hexose transportTASbiological_process
GO:0009566FertilizationIEAbiological_process
GO:0010827Regulation of glucose transportTASbiological_process
GO:0015758Glucose transportTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0031965Nuclear membraneIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046822Regulation of nucleocytoplasmic transportNASbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98096620190.02935565140.99999024730.3245149517

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0070050366
GSE13712_SHEARUp0.1491934097
GSE13712_STATICDown-0.1618131249
GSE19018Down-0.0212954788
GSE19899_A1Down-0.2761775064
GSE19899_A2Down-0.0349808366
PubMed_21979375_A1Down-0.5346111070
PubMed_21979375_A2Down-0.1118954364
GSE35957Down-0.4445096507
GSE36640Down-0.6808308775
GSE54402Down-0.3390455519
GSE9593Down-0.4289286694
GSE43922Down-0.0072578222
GSE24585Down-0.1653533458
GSE37065Down-0.1004356645
GSE28863_A1Down-0.1745399490
GSE28863_A2Up0.1237105786
GSE28863_A3Down-0.7387100083
GSE28863_A4Up0.0338460549
GSE48662Down-0.2477685663

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031962ProteomicsFunctional MTI (Weak)18668040
hsa-miR-1296-5pMIMAT0005794MIRT036148CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041345CLASHFunctional MTI (Weak)23622248
hsa-miR-28-5pMIMAT0000085MIRT049994CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.