HCSGD entry for JHDM1D
1. General information
| Official gene symbol | JHDM1D |
|---|---|
| Entrez ID | 80853 |
| Gene full name | jumonji C domain containing histone demethylase 1 homolog D (S. cerevisiae) |
| Other gene symbols | KDM7A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005506 | Iron ion binding | IDA TAS | molecular_function |
| GO:0005634 | Nucleus | IC IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IDA | molecular_function |
| GO:0016706 | Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors | IDA | molecular_function |
| GO:0030901 | Midbrain development | ISS | biological_process |
| GO:0032454 | Histone demethylase activity (H3-K9 specific) | IDA | molecular_function |
| GO:0033169 | Histone H3-K9 demethylation | IDA | biological_process |
| GO:0035064 | Methylated histone residue binding | IDA | molecular_function |
| GO:0035574 | Histone H4-K20 demethylation | IDA | biological_process |
| GO:0035575 | Histone demethylase activity (H4-K20 specific) | IDA | molecular_function |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0051864 | Histone demethylase activity (H3-K36 specific) | IDA | molecular_function |
| GO:0070544 | Histone H3-K36 demethylation | IDA | biological_process |
| GO:0071557 | Histone H3-K27 demethylation | IDA | biological_process |
| GO:0071558 | Histone demethylase activity (H3-K27 specific) | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0018834771 | 0.7533266175 | 0.1155594406 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2464400686 |
| GSE13712_SHEAR | Down | -0.3153564304 |
| GSE13712_STATIC | Down | -0.4846764526 |
| GSE19018 | Down | -0.0954286643 |
| GSE19899_A1 | Up | 0.4879557964 |
| GSE19899_A2 | Up | 1.4838584572 |
| PubMed_21979375_A1 | Up | 2.8908498414 |
| PubMed_21979375_A2 | Up | 1.2724798473 |
| GSE35957 | Up | 0.1571146904 |
| GSE36640 | Up | 0.8634988337 |
| GSE54402 | Up | 1.7539658788 |
| GSE9593 | Down | -0.2256004065 |
| GSE43922 | Up | 1.4578577432 |
| GSE24585 | Up | 0.3575111999 |
| GSE37065 | Up | 0.7193914127 |
| GSE28863_A1 | Up | 0.6581690429 |
| GSE28863_A2 | Up | 0.0823984577 |
| GSE28863_A3 | Down | -0.2179030042 |
| GSE28863_A4 | Down | -0.4524604894 |
| GSE48662 | Up | 0.6374463037 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017172 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029121 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
