HCSGD entry for COASY
1. General information
| Official gene symbol | COASY |
|---|---|
| Entrez ID | 80347 |
| Gene full name | CoA synthase |
| Other gene symbols | DPCK NBP PPAT UKR1 pOV-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004140 | Dephospho-CoA kinase activity | IDA IEA | molecular_function |
| GO:0004595 | Pantetheine-phosphate adenylyltransferase activity | IDA IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0009108 | Coenzyme biosynthetic process | TAS | biological_process |
| GO:0015937 | Coenzyme A biosynthetic process | IDA IEA TAS | biological_process |
| GO:0015939 | Pantothenate metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5588548915 | 0.1432959310 | 0.9999902473 | 0.7291111927 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3971769296 |
| GSE13712_SHEAR | Down | -0.2147012172 |
| GSE13712_STATIC | Down | -0.0201446150 |
| GSE19018 | Up | 0.1643296066 |
| GSE19899_A1 | Down | -0.2690594059 |
| GSE19899_A2 | Down | -0.4220269519 |
| PubMed_21979375_A1 | Down | -0.3904313853 |
| PubMed_21979375_A2 | Down | -0.4447011978 |
| GSE35957 | Down | -0.5972704497 |
| GSE36640 | Down | -0.3107389752 |
| GSE54402 | Up | 0.1894919429 |
| GSE9593 | Down | -0.4676342782 |
| GSE43922 | Up | 0.0350967569 |
| GSE24585 | Down | -0.5265038313 |
| GSE37065 | Down | -0.0794295557 |
| GSE28863_A1 | Up | 0.2008195748 |
| GSE28863_A2 | Up | 0.4186731215 |
| GSE28863_A3 | Up | 0.2657579218 |
| GSE28863_A4 | Up | 0.0702811991 |
| GSE48662 | Up | 0.3735477744 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030060 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-760 | MIMAT0004957 | MIRT036719 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043324 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050109 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
