HCSGD entry for ZKSCAN3
1. General information
| Official gene symbol | ZKSCAN3 |
|---|---|
| Entrez ID | 80317 |
| Gene full name | zinc finger with KRAB and SCAN domains 3 |
| Other gene symbols | ZF47 ZFP306 ZNF306 ZNF309 ZSCAN13 ZSCAN35 Zfp47 dJ874C20.1 dJ874C20.1. zfp-47 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006914 | Autophagy | IEA | biological_process |
| GO:0007040 | Lysosome organization | IMP | biological_process |
| GO:0010507 | Negative regulation of autophagy | IMP | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IDA | molecular_function |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:2000773 | Negative regulation of cellular senescence | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8648254854 | 0.2003428403 | 0.9999902473 | 0.8655981451 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0808038004 |
| GSE13712_SHEAR | Down | -0.1541590170 |
| GSE13712_STATIC | Down | -0.1237138245 |
| GSE19018 | Up | 0.0058746604 |
| GSE19899_A1 | Up | 0.0337627141 |
| GSE19899_A2 | Down | -0.3317118682 |
| PubMed_21979375_A1 | Down | -1.0788953906 |
| PubMed_21979375_A2 | Down | -0.2838436254 |
| GSE35957 | Down | -0.0487720864 |
| GSE36640 | Up | 0.4261360602 |
| GSE54402 | Down | -0.3217654824 |
| GSE9593 | Down | -0.0847440601 |
| GSE43922 | Down | -0.0026016938 |
| GSE24585 | Up | 0.4608286949 |
| GSE37065 | Up | 0.1129254470 |
| GSE28863_A1 | Up | 0.1697840805 |
| GSE28863_A2 | Down | -0.0375432169 |
| GSE28863_A3 | Down | -0.1854706963 |
| GSE28863_A4 | Down | -0.3115167191 |
| GSE48662 | Down | -0.0689376945 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029358 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
