HCSGD entry for CDK5RAP3
1. General information
| Official gene symbol | CDK5RAP3 |
|---|---|
| Entrez ID | 80279 |
| Gene full name | CDK5 regulatory subunit associated protein 3 |
| Other gene symbols | C53 HSF-27 IC53 LZAP MST016 OK/SW-cl.114 PP1553 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000079 | Regulation of cyclin-dependent protein serine/threonine kinase activity | ISS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0007420 | Brain development | NAS | biological_process |
| GO:0019901 | Protein kinase binding | NAS | molecular_function |
| GO:0045664 | Regulation of neuron differentiation | NAS | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0071569 | Protein ufmylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6480252270 | 0.1207679419 | 0.9999902473 | 0.6678010504 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.5080397942 |
| GSE13712_SHEAR | Down | -0.4661868507 |
| GSE13712_STATIC | Down | -0.3834750314 |
| GSE19018 | Up | 0.3101151549 |
| GSE19899_A1 | Down | -0.6472152102 |
| GSE19899_A2 | Down | -0.3595606285 |
| PubMed_21979375_A1 | Down | -0.5557925388 |
| PubMed_21979375_A2 | Down | -0.4517239003 |
| GSE35957 | Down | -0.4318156018 |
| GSE36640 | Down | -0.0258533851 |
| GSE54402 | Down | -0.1060094582 |
| GSE9593 | Down | -0.3529399099 |
| GSE43922 | Up | 0.0547456237 |
| GSE24585 | Up | 0.4298001594 |
| GSE37065 | Down | -0.0634761391 |
| GSE28863_A1 | Up | 0.0352205141 |
| GSE28863_A2 | Down | -0.0744555439 |
| GSE28863_A3 | Up | 0.0777928234 |
| GSE28863_A4 | Up | 0.1329635898 |
| GSE48662 | Up | 0.2207219974 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001561 | pSILAC | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT001561 | Proteomics;Other | Functional MTI (Weak) | 20584899 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-379-5p | MIMAT0000733 | 1 | hsa-miR-379 | 21394385 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
