HCSGD entry for ORAI2


1. General information

Official gene symbolORAI2
Entrez ID80228
Gene full nameORAI calcium release-activated calcium modulator 2
Other gene symbolsC7orf19 CBCIP2 MEM142B TMEM142B
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0016021Integral component of membraneIEAcellular_component
GO:0030426Growth coneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.33909816120.50502460770.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1762326816
GSE13712_SHEARDown-0.0382651001
GSE13712_STATICDown-0.1995434670
GSE19018Down-0.0688228307
GSE19899_A1Up0.0658394330
GSE19899_A2Up0.4932064819
PubMed_21979375_A1Down-0.2862324908
PubMed_21979375_A2Up0.5372814906
GSE35957Down-0.2592490947
GSE36640Up0.0866785621
GSE54402Up0.5933874141
GSE9593Up0.1672837082
GSE43922Up0.0111411549
GSE24585Down-0.0470736029
GSE37065Down-0.3587611963
GSE28863_A1Down-0.3057873064
GSE28863_A2Down-0.0377486755
GSE28863_A3Down-0.0773800663
GSE28863_A4Down-0.1242984831
GSE48662Up0.4539455678

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT042351CLASHFunctional MTI (Weak)23622248
hsa-miR-320aMIMAT0000510MIRT044701CLASHFunctional MTI (Weak)23622248
hsa-miR-10b-5pMIMAT0000254MIRT047449CLASHFunctional MTI (Weak)23622248
hsa-miR-10a-5pMIMAT0000253MIRT047579CLASHFunctional MTI (Weak)23622248
hsa-miR-16-5pMIMAT0000069MIRT051095CLASHFunctional MTI (Weak)23622248
hsa-let-7a-5pMIMAT0000062MIRT052447CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.