HCSGD entry for LHX3

1. General information

Official gene symbolLHX3
Entrez ID8022
Gene full nameLIM homeobox 3
Other gene symbolsCPHD3 LIM3 M2-LHX3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001076RNA polymerase II transcription factor binding transcription factor activityIEAmolecular_function
GO:0001890Placenta developmentIEAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005667Transcription factor complexIEAcellular_component
GO:0008045Motor neuron axon guidanceIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009887Organ morphogenesisTASbiological_process
GO:0021520Spinal cord motor neuron cell fate specificationIEAbiological_process
GO:0021521Ventral spinal cord interneuron specificationIEAbiological_process
GO:0021526Medial motor column neuron differentiationIEAbiological_process
GO:0021527Spinal cord association neuron differentiationIEAbiological_process
GO:0021983Pituitary gland developmentIEAbiological_process
GO:0030324Lung developmentIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0048839Inner ear developmentIEPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.49885128600.86858308570.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1485602999
GSE13712_SHEARUp0.0457207669
GSE13712_STATICUp0.1667012261
GSE19018Down-0.1912590905
GSE19899_A1Up0.1062845941
GSE19899_A2Up0.1140731049
PubMed_21979375_A1Up0.1937507920
PubMed_21979375_A2Down-0.1224361275
GSE35957Up0.2967970163
GSE36640Up0.1145194260
GSE54402Up0.0410883100
GSE9593Up0.0429902917
GSE43922Up0.0728668075
GSE24585Up0.0755883306
GSE37065Down-0.1591622765
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.1132917182

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.