HCSGD entry for BRD3
1. General information
| Official gene symbol | BRD3 |
|---|---|
| Entrez ID | 8019 |
| Gene full name | bromodomain containing 3 |
| Other gene symbols | ORFX RING3L |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003682 | Chromatin binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0070577 | Histone acetyl-lysine binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5291393488 | 0.1221263554 | 0.9999902473 | 0.6702434946 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0353370048 |
| GSE13712_SHEAR | Down | -0.3971553336 |
| GSE13712_STATIC | Down | -0.3886978563 |
| GSE19018 | Up | 0.1112414805 |
| GSE19899_A1 | Down | -0.5559283696 |
| GSE19899_A2 | Down | -0.5876845483 |
| PubMed_21979375_A1 | Down | -0.6717442782 |
| PubMed_21979375_A2 | Down | -0.7936000078 |
| GSE35957 | Down | -0.4935039764 |
| GSE36640 | Down | -0.3146133953 |
| GSE54402 | Down | -0.0587911900 |
| GSE9593 | Down | -0.0337905373 |
| GSE43922 | Up | 0.0445105789 |
| GSE24585 | Up | 0.6206687737 |
| GSE37065 | Down | -0.1499443940 |
| GSE28863_A1 | Up | 0.3819573753 |
| GSE28863_A2 | Up | 0.1678310359 |
| GSE28863_A3 | Up | 0.4475184766 |
| GSE28863_A4 | Up | 0.0424293592 |
| GSE48662 | Up | 0.5712081430 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-141-3p | MIMAT0000432 | MIRT003279 | Luciferase reporter assay//Western blot//Reporter assay;Western blot;Other | Functional MTI | 20053927 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT004162 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029195 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
