HCSGD entry for ASRGL1
1. General information
| Official gene symbol | ASRGL1 |
|---|---|
| Entrez ID | 80150 |
| Gene full name | asparaginase like 1 |
| Other gene symbols | ALP ALP1 CRASH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003948 | N4-(beta-N-acetylglucosaminyl)-L-asparaginase activity | IDA | molecular_function |
| GO:0004067 | Asparaginase activity | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008798 | Beta-aspartyl-peptidase activity | IDA | molecular_function |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0033345 | Asparagine catabolic process via L-aspartate | IDA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5312459557 | 0.5911677178 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1014687940 |
| GSE13712_SHEAR | Down | -0.8283010590 |
| GSE13712_STATIC | Down | -0.4625114954 |
| GSE19018 | Up | 0.0283005410 |
| GSE19899_A1 | Up | 0.1142654802 |
| GSE19899_A2 | Up | 0.0958698508 |
| PubMed_21979375_A1 | Up | 0.1983188323 |
| PubMed_21979375_A2 | Down | -0.1453365076 |
| GSE35957 | Down | -0.0491272861 |
| GSE36640 | Down | -0.0183976760 |
| GSE54402 | Down | -0.0252923865 |
| GSE9593 | Up | 0.0669986993 |
| GSE43922 | Up | 0.0233794441 |
| GSE24585 | Up | 0.2305237428 |
| GSE37065 | Down | -0.0562333366 |
| GSE28863_A1 | Down | -0.0980008434 |
| GSE28863_A2 | Up | 0.0342145684 |
| GSE28863_A3 | Up | 0.2391220716 |
| GSE28863_A4 | Up | 0.0113807218 |
| GSE48662 | Up | 0.2508315063 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| L-Aspartic Acid | DB00128 | NUTR00016 | EXPT01823 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-215-5p | MIMAT0000272 | MIRT024570 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026301 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030736 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
