HCSGD entry for SIKE1
1. General information
| Official gene symbol | SIKE1 |
|---|---|
| Entrez ID | 80143 |
| Gene full name | suppressor of IKBKE 1 |
| Other gene symbols | SIKE |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0045087 | Innate immune response | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9770076479 | 0.0477414194 | 0.9999902473 | 0.4095152945 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2124877443 |
| GSE13712_SHEAR | Down | -0.1299704295 |
| GSE13712_STATIC | Down | -0.0743149365 |
| GSE19018 | Down | -0.4351735859 |
| GSE19899_A1 | Down | -0.0194893391 |
| GSE19899_A2 | Down | -0.5521000088 |
| PubMed_21979375_A1 | Down | -0.1476491480 |
| PubMed_21979375_A2 | Up | 0.1498551274 |
| GSE35957 | Up | 0.0654538638 |
| GSE36640 | Down | -0.0749730665 |
| GSE54402 | Down | -0.3322150469 |
| GSE9593 | Down | -0.0264354968 |
| GSE43922 | Down | -0.0228107815 |
| GSE24585 | Up | 0.3054644219 |
| GSE37065 | Down | -0.0901571720 |
| GSE28863_A1 | Down | -0.4497559129 |
| GSE28863_A2 | Down | -0.0198779064 |
| GSE28863_A3 | Down | -0.6466566083 |
| GSE28863_A4 | Down | -0.2623349965 |
| GSE48662 | Up | 0.0370137281 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT052225 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
