HCSGD entry for ZNF703


1. General information

Official gene symbolZNF703
Entrez ID80139
Gene full namezinc finger protein 703
Other gene symbolsZEPPO1 ZNF503L ZPO1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDA ISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIDAbiological_process
GO:0008284Positive regulation of cell proliferationIDAbiological_process
GO:0010718Positive regulation of epithelial to mesenchymal transitionISSbiological_process
GO:0016363Nuclear matrixIDAcellular_component
GO:0017015Regulation of transforming growth factor beta receptor signaling pathwayIDAbiological_process
GO:0030335Positive regulation of cell migrationISSbiological_process
GO:0033601Positive regulation of mammary gland epithelial cell proliferationIDAbiological_process
GO:0034111Negative regulation of homotypic cell-cell adhesionISSbiological_process
GO:0034333Adherens junction assemblyISSbiological_process
GO:0043234Protein complexIDAcellular_component
GO:0045892Negative regulation of transcription, DNA-templatedIMPbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0051726Regulation of cell cycleIDAbiological_process
GO:0060644Mammary gland epithelial cell differentiationIDAbiological_process
GO:0060828Regulation of canonical Wnt signaling pathwayISSbiological_process
GO:0070491Repressing transcription factor bindingIEAmolecular_function
GO:0071392Cellular response to estradiol stimulusIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72050064210.02280463130.99999024730.2904135462

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.7507780297
GSE13712_SHEARDown-0.1359682814
GSE13712_STATICDown-0.0586604522
GSE19018Down-0.2828897611
GSE19899_A1Down-0.2429538303
GSE19899_A2Up0.0570257902
PubMed_21979375_A1Up0.0087825597
PubMed_21979375_A2Down-0.2739182582
GSE35957Down-0.2676197946
GSE36640Down-0.1385472572
GSE54402Down-1.4300404622
GSE9593Down-0.7495739074
GSE43922Up0.0673693849
GSE24585Up0.9637462323
GSE37065Down-0.3716375929
GSE28863_A1Up0.2109352839
GSE28863_A2Up0.2338132164
GSE28863_A3Up0.2628679171
GSE28863_A4Down-0.1149758946
GSE48662Down-0.0244568495

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-760MIMAT0004957MIRT036709CLASHFunctional MTI (Weak)23622248
hsa-miR-296-3pMIMAT0004679MIRT038483CLASHFunctional MTI (Weak)23622248
hsa-miR-93-3pMIMAT0004509MIRT038858CLASHFunctional MTI (Weak)23622248
hsa-miR-542-5pMIMAT0003340MIRT039352CLASHFunctional MTI (Weak)23622248
hsa-miR-425-3pMIMAT0001343MIRT042430CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049534CLASHFunctional MTI (Weak)23622248
hsa-miR-26a-5pMIMAT0000082MIRT050098CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-5pMIMAT0000072MIRT050650CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.