HCSGD entry for PGAP1
1. General information
| Official gene symbol | PGAP1 |
|---|---|
| Entrez ID | 80055 |
| Gene full name | post-GPI attachment to proteins 1 |
| Other gene symbols | Bst1 ISPD3024 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004518 | Nuclease activity | ISS | molecular_function |
| GO:0005783 | Endoplasmic reticulum | ISS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0006501 | C-terminal protein lipidation | TAS | biological_process |
| GO:0006505 | GPI anchor metabolic process | IEA | biological_process |
| GO:0006886 | Intracellular protein transport | IEA | biological_process |
| GO:0007605 | Sensory perception of sound | IEA | biological_process |
| GO:0009880 | Embryonic pattern specification | IEA | biological_process |
| GO:0009948 | Anterior/posterior axis specification | IEA | biological_process |
| GO:0015798 | Myo-inositol transport | ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016255 | Attachment of GPI anchor to protein | TAS | biological_process |
| GO:0016788 | Hydrolase activity, acting on ester bonds | IEA | molecular_function |
| GO:0021871 | Forebrain regionalization | IEA | biological_process |
| GO:0042578 | Phosphoric ester hydrolase activity | ISS | molecular_function |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0060322 | Head development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5921622507 | 0.0622773945 | 0.9999902473 | 0.4707648765 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0763591595 |
| GSE13712_SHEAR | Down | -0.2421071645 |
| GSE13712_STATIC | Up | 0.2497616170 |
| GSE19018 | Down | -0.1776897272 |
| GSE19899_A1 | Down | -0.0597554537 |
| GSE19899_A2 | Down | -0.8275571825 |
| PubMed_21979375_A1 | Up | 0.0784728847 |
| PubMed_21979375_A2 | Down | -0.3672659829 |
| GSE35957 | Down | -0.0419436997 |
| GSE36640 | Down | -0.9638494942 |
| GSE54402 | Down | -0.5493938147 |
| GSE9593 | Down | -0.1538402352 |
| GSE43922 | Up | 0.0376765828 |
| GSE24585 | Up | 0.6525287294 |
| GSE37065 | Up | 0.5454336150 |
| GSE28863_A1 | Up | 0.5342489677 |
| GSE28863_A2 | Up | 0.2802024360 |
| GSE28863_A3 | Down | -0.8958937154 |
| GSE28863_A4 | Down | -0.2841584708 |
| GSE48662 | Up | 0.0925189562 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-590-3p | MIMAT0004801 | MIRT016203 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
