HCSGD entry for PHC3
1. General information
| Official gene symbol | PHC3 |
|---|---|
| Entrez ID | 80012 |
| Gene full name | polyhomeotic homolog 3 (Drosophila) |
| Other gene symbols | EDR3 HPH3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0007275 | Multicellular organismal development | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0031519 | PcG protein complex | IDA | cellular_component |
| GO:0035102 | PRC1 complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4408554424 | 0.5239880970 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0131777699 |
| GSE13712_SHEAR | Up | 0.2174964235 |
| GSE13712_STATIC | Up | 0.1205761315 |
| GSE19018 | Down | -0.1072180810 |
| GSE19899_A1 | Up | 0.0236410556 |
| GSE19899_A2 | Up | 0.2916988886 |
| PubMed_21979375_A1 | Up | 0.2053281035 |
| PubMed_21979375_A2 | Up | 0.4140589348 |
| GSE35957 | Up | 0.1317471945 |
| GSE36640 | Up | 0.1360294630 |
| GSE54402 | Down | -0.1345811039 |
| GSE9593 | Down | -0.0464715489 |
| GSE43922 | Down | -0.1373584381 |
| GSE24585 | Down | -0.1148902223 |
| GSE37065 | Up | 0.1465071357 |
| GSE28863_A1 | Up | 0.2333992005 |
| GSE28863_A2 | Up | 0.2453707649 |
| GSE28863_A3 | Down | -0.6820709771 |
| GSE28863_A4 | Down | -0.3767313524 |
| GSE48662 | Up | 0.2300208258 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-218-5p | MIMAT0000275 | MIRT024226 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026037 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027049 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027998 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031784 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
