HCSGD entry for DENND2D
1. General information
| Official gene symbol | DENND2D |
|---|---|
| Entrez ID | 79961 |
| Gene full name | DENN/MADD domain containing 2D |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8689783747 | 0.2158856122 | 0.9999902473 | 0.8956275346 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0925127016 |
| GSE13712_SHEAR | Down | -0.3278343792 |
| GSE13712_STATIC | Down | -0.1439674143 |
| GSE19018 | Up | 0.0311954238 |
| GSE19899_A1 | Up | 0.1109304223 |
| GSE19899_A2 | Up | 0.0123426516 |
| PubMed_21979375_A1 | Down | -0.1892599223 |
| PubMed_21979375_A2 | Down | -0.1584909780 |
| GSE35957 | Down | -0.0241107503 |
| GSE36640 | Down | -0.5672448450 |
| GSE54402 | Down | -0.5609741865 |
| GSE9593 | Up | 0.2501286198 |
| GSE43922 | Up | 0.0234236673 |
| GSE24585 | Up | 0.0511705670 |
| GSE37065 | Up | 0.2698086667 |
| GSE28863_A1 | Down | -0.4228561525 |
| GSE28863_A2 | Up | 0.1379907996 |
| GSE28863_A3 | Up | 0.0983596912 |
| GSE28863_A4 | Down | -0.0858714727 |
| GSE48662 | Up | 0.3999703990 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022403 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
