HCSGD entry for TUSC3
1. General information
| Official gene symbol | TUSC3 |
|---|---|
| Entrez ID | 7991 |
| Gene full name | tumor suppressor candidate 3 |
| Other gene symbols | D8S1992 M33 MRT22 MRT7 N33 OST3A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004579 | Dolichyl-diphosphooligosaccharide-protein glycotransferase activity | ISS | molecular_function |
| GO:0005739 | Mitochondrion | ISS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | NAS | cellular_component |
| GO:0006487 | Protein N-linked glycosylation | NAS | biological_process |
| GO:0008250 | Oligosaccharyltransferase complex | IDA | cellular_component |
| GO:0015095 | Magnesium ion transmembrane transporter activity | IMP | molecular_function |
| GO:0015693 | Magnesium ion transport | IGI IMP | biological_process |
| GO:0018279 | Protein N-linked glycosylation via asparagine | ISS TAS | biological_process |
| GO:0034220 | Ion transmembrane transport | IMP | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
| GO:0050890 | Cognition | IMP | biological_process |
| GO:0055085 | Transmembrane transport | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6247821283 | 0.0437450705 | 0.9999902473 | 0.3935823369 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0751582554 |
| GSE13712_SHEAR | Down | -0.6230284542 |
| GSE13712_STATIC | Down | -0.7312634306 |
| GSE19018 | Up | 0.9689036859 |
| GSE19899_A1 | Up | 0.3083462099 |
| GSE19899_A2 | Up | 0.0603054819 |
| PubMed_21979375_A1 | Down | -0.5656145383 |
| PubMed_21979375_A2 | Down | -0.1350089274 |
| GSE35957 | Down | -0.9594333778 |
| GSE36640 | Down | -0.2194548854 |
| GSE54402 | Down | -0.3090897541 |
| GSE9593 | Up | 0.2760238853 |
| GSE43922 | Up | 0.0227055847 |
| GSE24585 | Up | 0.2622904447 |
| GSE37065 | Up | 0.0087163767 |
| GSE28863_A1 | Down | -0.5263895105 |
| GSE28863_A2 | Up | 0.0509672065 |
| GSE28863_A3 | Down | -0.5209924389 |
| GSE28863_A4 | Down | -0.2416644659 |
| GSE48662 | Up | 0.0786172431 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-128-3p | MIMAT0000424 | MIRT022014 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029507 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036380 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-25-3p | MIMAT0000081 | MIRT050240 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
