HCSGD entry for PEAK1
1. General information
| Official gene symbol | PEAK1 |
|---|---|
| Entrez ID | 79834 |
| Gene full name | NKF3 kinase family member |
| Other gene symbols | SGK269 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004715 | Non-membrane spanning protein tyrosine kinase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005925 | Focal adhesion | IDA IEA | cellular_component |
| GO:0015629 | Actin cytoskeleton | IDA IEA | cellular_component |
| GO:0016477 | Cell migration | IDA | biological_process |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | IDA | biological_process |
| GO:0034446 | Substrate adhesion-dependent cell spreading | IDA | biological_process |
| GO:0046777 | Protein autophosphorylation | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0872424414 | 0.1282320543 | 0.6197985965 | 0.6900829892 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.6630555392 |
| GSE13712_SHEAR | Down | -0.0554865407 |
| GSE13712_STATIC | Up | 0.0557359231 |
| GSE19018 | Down | -0.0410730404 |
| GSE19899_A1 | Down | -0.7090418233 |
| GSE19899_A2 | Down | -0.0660569614 |
| PubMed_21979375_A1 | Down | -0.8895090884 |
| PubMed_21979375_A2 | Down | -0.0168381160 |
| GSE35957 | Up | 0.6217947301 |
| GSE36640 | Down | -0.4319202992 |
| GSE54402 | Down | -0.4418092065 |
| GSE9593 | Up | 0.1521318516 |
| GSE43922 | Down | -0.1950753731 |
| GSE24585 | Up | 0.2632224502 |
| GSE37065 | Down | -0.1375874459 |
| GSE28863_A1 | Up | 1.3973528329 |
| GSE28863_A2 | Up | 0.9971146178 |
| GSE28863_A3 | Up | 0.5349620885 |
| GSE28863_A4 | Down | -0.0136998321 |
| GSE48662 | Up | 0.3380349059 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-183-5p | MIMAT0000261 | MIRT025011 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord

