HCSGD entry for AGMAT


1. General information

Official gene symbolAGMAT
Entrez ID79814
Gene full nameagmatine ureohydrolase (agmatinase)
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005739MitochondrionTAScellular_component
GO:0006595Polyamine metabolic processTASbiological_process
GO:0008295Spermidine biosynthetic processIEAbiological_process
GO:0008783Agmatinase activityIEAmolecular_function
GO:0033388Putrescine biosynthetic process from arginineIEAbiological_process
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0097055Agmatine biosynthetic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.32817412710.49144078870.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0412368736
GSE13712_SHEARUp0.0727786529
GSE13712_STATICUp0.4158479606
GSE19018Down-0.3878758138
GSE19899_A1Up0.1499928384
GSE19899_A2Up0.8373355453
PubMed_21979375_A1Up0.1041429753
PubMed_21979375_A2Up0.5997837714
GSE35957Down-0.4586980116
GSE36640Down-0.2052308281
GSE54402Up0.2212475937
GSE9593Down-0.4575664701
GSE43922Up0.0827353394
GSE24585Up0.1013231540
GSE37065Down-0.2055370594
GSE28863_A1Down-0.1472254302
GSE28863_A2Down-0.0260619931
GSE28863_A3Up0.0617206516
GSE28863_A4Up0.0888301959
GSE48662Down-0.4257725627

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT001392pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-26b-5pMIMAT0000083MIRT029705MicroarrayFunctional MTI (Weak)19088304
hsa-let-7e-5pMIMAT0000066MIRT051619CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.