HCSGD entry for TFPI2
1. General information
| Official gene symbol | TFPI2 |
|---|---|
| Entrez ID | 7980 |
| Gene full name | tissue factor pathway inhibitor 2 |
| Other gene symbols | PP5 REF1 TFPI-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IEA | molecular_function |
| GO:0005201 | Extracellular matrix structural constituent | TAS | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | TAS | cellular_component |
| GO:0007596 | Blood coagulation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0012089016 | 0.0161451845 | 0.0935867647 | 0.2477452214 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8259647758 |
| GSE13712_SHEAR | Down | -1.9333324224 |
| GSE13712_STATIC | Down | -1.6019934999 |
| GSE19018 | Up | 1.7868723261 |
| GSE19899_A1 | Up | 0.4031305756 |
| GSE19899_A2 | Up | 1.1992166699 |
| PubMed_21979375_A1 | Up | 2.0938868982 |
| PubMed_21979375_A2 | Up | 1.2285230500 |
| GSE35957 | Down | -3.8867880964 |
| GSE36640 | Down | -1.6304738356 |
| GSE54402 | Up | 0.1154078289 |
| GSE9593 | Down | -0.5467235722 |
| GSE43922 | Up | 2.5865992420 |
| GSE24585 | Up | 0.9235823143 |
| GSE37065 | Up | 1.8762955362 |
| GSE28863_A1 | Down | -0.9613560668 |
| GSE28863_A2 | Up | 0.4966863661 |
| GSE28863_A3 | Up | 0.0428078050 |
| GSE28863_A4 | Down | -0.4589447112 |
| GSE48662 | Up | 0.1351886156 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-616-3p | MIMAT0004805 | MIRT005774 | In situ hybridization//Luciferase reporter assay//Microarray//qRT-PCR | Functional MTI | 21224345 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-616-3p | MIMAT0004805 | 1 | hsa-miR-616 | 21224345 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
