HCSGD entry for PALB2
1. General information
| Official gene symbol | PALB2 |
|---|---|
| Entrez ID | 79728 |
| Gene full name | partner and localizer of BRCA2 |
| Other gene symbols | FANCN PNCA3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000724 | Double-strand break repair via homologous recombination | IDA | biological_process |
| GO:0001756 | Somitogenesis | IEA | biological_process |
| GO:0001833 | Inner cell mass cell proliferation | IEA | biological_process |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0006281 | DNA repair | TAS | biological_process |
| GO:0007498 | Mesoderm development | IEA | biological_process |
| GO:0009887 | Organ morphogenesis | IEA | biological_process |
| GO:0036342 | Post-anal tail morphogenesis | IEA | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5320190076 | 0.2064197941 | 0.9999902473 | 0.8810078482 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3812820424 |
| GSE13712_SHEAR | Down | -0.1416562243 |
| GSE13712_STATIC | Down | -0.0383244982 |
| GSE19018 | Down | -0.3118489845 |
| GSE19899_A1 | Up | 0.0103663304 |
| GSE19899_A2 | Down | -0.1555286128 |
| PubMed_21979375_A1 | Up | 0.0002807343 |
| PubMed_21979375_A2 | Down | -0.1228893357 |
| GSE35957 | Down | -0.1521373226 |
| GSE36640 | Down | -0.5123468304 |
| GSE54402 | Up | 0.2229530090 |
| GSE9593 | Down | -0.0928874872 |
| GSE43922 | Up | 0.0633178818 |
| GSE24585 | Up | 0.0351553783 |
| GSE37065 | Up | 0.1349996999 |
| GSE28863_A1 | Down | -0.0516760033 |
| GSE28863_A2 | Up | 0.2858175452 |
| GSE28863_A3 | Down | -0.6843960456 |
| GSE28863_A4 | Up | 0.1758059158 |
| GSE48662 | Down | -0.5666188865 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT046846 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
