HCSGD entry for PLEKHF2
1. General information
| Official gene symbol | PLEKHF2 |
|---|---|
| Entrez ID | 79666 |
| Gene full name | pleckstrin homology domain containing, family F (with FYVE domain) member 2 |
| Other gene symbols | EAPF PHAFIN2 ZFYVE18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0030133 | Transport vesicle | IDA | cellular_component |
| GO:0031901 | Early endosome membrane | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9229219141 | 0.0062949812 | 0.9999902473 | 0.1617048591 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2431535495 |
| GSE13712_SHEAR | Up | 0.1579667675 |
| GSE13712_STATIC | Down | -0.1514739252 |
| GSE19018 | Up | 0.4079247004 |
| GSE19899_A1 | Down | -0.9948474421 |
| GSE19899_A2 | Down | -1.0140155090 |
| PubMed_21979375_A1 | Down | -1.0716523176 |
| PubMed_21979375_A2 | Down | -1.3490120063 |
| GSE35957 | Down | -0.4886063173 |
| GSE36640 | Up | 0.1393169748 |
| GSE54402 | Down | -0.2201639450 |
| GSE9593 | Up | 0.3150772559 |
| GSE43922 | Down | -0.8395625568 |
| GSE24585 | Down | -0.0164600262 |
| GSE37065 | Up | 0.2332419931 |
| GSE28863_A1 | Down | -0.7386083963 |
| GSE28863_A2 | Down | -0.0558768738 |
| GSE28863_A3 | Down | -0.9632000217 |
| GSE28863_A4 | Down | -0.3491450182 |
| GSE48662 | Down | -0.0987311246 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022986 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024767 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026780 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
