HCSGD entry for RHBDF2
1. General information
| Official gene symbol | RHBDF2 |
|---|---|
| Entrez ID | 79651 |
| Gene full name | rhomboid 5 homolog 2 (Drosophila) |
| Other gene symbols | RHBDL5 RHBDL6 TOC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004252 | Serine-type endopeptidase activity | IEA | molecular_function |
| GO:0005789 | Endoplasmic reticulum membrane | IEA ISS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0019838 | Growth factor binding | IEA | molecular_function |
| GO:0050709 | Negative regulation of protein secretion | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0036948406 | 0.9815518711 | 0.1631743289 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0893964642 |
| GSE13712_SHEAR | Up | 1.6394930131 |
| GSE13712_STATIC | Up | 0.9677726946 |
| GSE19018 | Up | 0.6438732234 |
| GSE19899_A1 | Up | 0.1855705413 |
| GSE19899_A2 | Up | 1.2460236231 |
| PubMed_21979375_A1 | Up | 1.6319961211 |
| PubMed_21979375_A2 | Up | 0.8122399510 |
| GSE35957 | Down | -0.4192747626 |
| GSE36640 | Up | 0.0609866949 |
| GSE54402 | Up | 0.3977077937 |
| GSE9593 | Up | 0.3012523096 |
| GSE43922 | Up | 0.3977836746 |
| GSE24585 | Down | -0.0958459423 |
| GSE37065 | Up | 0.2799828688 |
| GSE28863_A1 | Down | -0.1479284337 |
| GSE28863_A2 | Up | 0.3867630674 |
| GSE28863_A3 | Up | 0.1074189124 |
| GSE28863_A4 | Down | -0.0473890890 |
| GSE48662 | Up | 0.6335658339 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017408 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025648 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027569 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039628 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
