HCSGD entry for MMEL1
1. General information
| Official gene symbol | MMEL1 |
|---|---|
| Entrez ID | 79258 |
| Gene full name | membrane metallo-endopeptidase-like 1 |
| Other gene symbols | MMEL2 NEP2 NEPII NL1 NL2 SEP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6011085141 | 0.8351850918 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0694500129 |
| GSE13712_SHEAR | Up | 0.0255048785 |
| GSE13712_STATIC | Down | -0.0509056781 |
| GSE19018 | Down | -0.0698419874 |
| GSE19899_A1 | Up | 0.1906831693 |
| GSE19899_A2 | Up | 0.1294306455 |
| PubMed_21979375_A1 | Up | 0.7984475378 |
| PubMed_21979375_A2 | Down | -0.1230648289 |
| GSE35957 | Up | 0.1106361794 |
| GSE36640 | Down | -0.0338402795 |
| GSE54402 | Up | 0.1132458996 |
| GSE9593 | Up | 0.0425945160 |
| GSE43922 | Up | 0.0114439738 |
| GSE24585 | Down | -0.0267890648 |
| GSE37065 | Down | -0.0943234199 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0225380665 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018444 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
